Anadrol-50 (Tablet)

 ANADROL(oxymetholone) Tablets for oral administration each contain 50 mg of the steroid oxymetholone, a potent anabolic and androgenic drug, oxymetholone is white to creamy white, crystalline powder. Practically insoluble in water, freely soluble in chloroform, soluble in dioxane, sparingly soluble in alcohol and slightly in water.
When there is sufficient intake of calories and protein, nitrogen balance is improved with anabolic agents but only. It has not been established if this positive nitrogen balance is of primary benefit in the utilization of protein-building dietary substances. ANADROL enhances the production and urinary excretion of erythropoietin in patients with anemias due to bone marrow failure and often stimulates erythropoiesis in anemias due to deficient red cell production.
The androgenic properties of this class of drugs was demonstrated by some certain clinical effects and adverse reactions. Complete dissociation of anabolic and androgenic effects has not been achieved. The actions of anabolic steroids are therefore similar to those of male sex hormones with the possibility of causing serious disturbances of growth and sexual development if given to young children. They suppress the gonadotropic functions of the pituitary and may affect the testes directly.
Indications and usage:
ANADROL Tablets is generally used for the treatment of anemias caused by deficient red cell production. Acquired aplastic anemia, congenital aplastic anemia, myelofibrosis and the hypoplastic anemias due to the administration of myelotoxic drugs often respond. ANADROL Tablets should not replace other supportive measures such as transfusion, correction of iron, folic acid, vitamin B12 or pyridoxine deficiency, antibacterial therapy and the appropriate use of corticosteroids.
Dosage and administration:
Usually, the effective dose is 1-2 mg/kg/day but higher doses may be required, and the dose should be individualized. Response is not often immediate, and a minimum trial of three to six months should be given. The dose in Children and adults is recommended daily 1-5 mg/kg body weight per day. Following remission, some patients may be maintained without the drug; others may be maintained on an established lower daily dosage. It is usually necessary for patients with congenital aplastic anemia to take a continued maintenance dose.
1. Male patients with carcinoma of the prostate or breast.
2. Females with hypercalcemia carcinoma of the breast; androgenic anabolic steroids may stimulate osteolytic resorption of bones.
3. Fetal harm will be cuased oxymetholone by when administered to pregnant women.
4. Nephrosis or the nephrotic phase of nephritis.
5. Hypersensitivity to the drug.
6. Severe hepatic dysfunction.